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In a key secondary endpoint, more than 65% of participants taking the highest dose of orforglipron achieved an A1C less than or equal to 6.5%, which is below the American Diabetes Association's (ADA) defined threshold for diabetes

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Many things cause excess uric acid in the body including kidney problems, liver problems, obesity, thyroid problems, an unhealthy diet, or a diet high in purine-containing foods such as fructose, meat, and alcohol

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